Looking for some of the best hotels in Florida Keys? There are many accommodation options to choose from, whether you are looking for a hotel, motel, campground, or condo.
If you’re looking for a luxurious experience, there are several high-end resorts located in the Keys. These resorts offer beautiful views of the ocean and access to all sorts of on-site amenities, like golf courses, spas, and restaurants.

If you’re on a budget, there are also plenty of affordable options available. You can find hotels and motels starting at around $70 per night, and campgrounds for as low as $20 per night. Some of the best hotels in Florida Keys we have on the list below are mid to high range, with prices around $300-$700 per night.
If you’re interested in renting a condo, there are many complexes available that offer beachfront access and all the amenities you could need, like pools and tennis courts.
Which of the Florida Keys is best for vacation?
The Florida Keys are a chain of islands located off the southern tip of Florida. They are a popular vacation destination, with something for everyone. It is one of the most popular destinations when looking for a long weekend getaway in the USA. Whether you’re looking for a quiet getaway or an action-packed adventure, the Keys have something to offer.
Big Pine Key
Big Pine Key is one of the better-known and very popular Florida Keys. It’s well known for its beautiful white-sand beaches, crystal clear waters, and abundance of coral reefs. It’s also a very isolated island, which makes it perfect for those looking for a romantic getaway. There are no high-rise hotels or crowds of tourists here – just miles of uninhabited beaches and quiet coves.
The beaches here are beautiful, and there is plenty of fishing, kayaking, and swimming to keep visitors busy. If you’re looking for a quiet place to get away from it all, Big Pine Key is the perfect spot.
Key Largo
If you’re looking for an unforgettable adventure vacation that’s both exotic and beautiful, look no further than Key Largo. Located in the heart of the Florida Keys, Key Largo is one of the most popular tourist destinations in the state. From its crystal clear waters to its lush tropical vegetation, Key Largo is a natural paradise. And with world-class fishing, diving, and snorkeling available right offshore, it’s no wonder that this island is a favorite destination for adventurous couples.
There’s no shortage of things to do in Key Largo. You can explore the many nature trails that wind through the island’s forests, go kayaking or canoeing on the tranquil waterways, or go diving and snorkeling to explore the incredible coral reefs.
Islamorada
Islamorada and Key West are two of the most popular Florida Keys. Islamorada is known as the sportfishing capital of the world, and Key West is known for its nightlife and shopping. Both keys offer beautiful beaches, coral reefs, and plenty of activities to keep visitors busy.
Islamorada is located about halfway between Miami and Key West, making it a convenient stop for those traveling in either direction. The key is home to many resorts, restaurants, and charter boat companies. Anglers will find plenty of opportunities to catch tarpon, bonefish, permit, and barracuda.
Key West
Key West is by far the best of the Florida Keys. It is definitely the most famous of them all. If you’re looking for a laid-back and boutique stay in the Florida Keys, Key West is the place for you.
There’s no shortage of things to do in this vibrant and eclectic city, from exploring Duval Street’s art galleries and restaurants to taking a sunset cruise or diving into the crystal-clear waters of the Atlantic Ocean. And with its small size, Key West is easy to explore on foot.
Accommodations in Key West range from luxurious resorts to quaint bed-and-breakfasts, so there’s something for everyone. This is the island where you can find the best hotels in Florida Keys. The island’s many art galleries and boutiques are also perfect for shopping enthusiasts. Be sure to taste some of Key West’s famous seafood, too – from fresh fish tacos to conch fritters, you won’t be disappointed!
Marathon
If you’re looking for a place to get away from it all, Marathon Island is the perfect spot. Located in the heart of the Florida Keys, this island is known for its stunning beaches and crystal clear waters. Whether you’re looking to go fishing, snorkeling, or just relax on the beach, Marathon Island has something for everyone.
One of the best things about Marathon Island is its accessibility. The island is only a short drive from Miami and Key West, making it easy to get to. You can also take a ferry from Key West to Marathon Island if you’re looking for a more scenic route.
If you’re looking for a place to relax and escape the hustle and bustle of everyday life, Marathon Island is definitely worth checking out. With its white sand beaches and crystal clear waters, this island is sure to charm you!
What are the 7 Best Hotels in Florida Keys?
Picking the right Florida Keys island to stay on can be tough. Do you want to relax and get away from it all? Big Pine Key is perfect for you. Prefer a little more adventure? Key Largo is the place for you. Want to relax in a laid-back and boutique setting? Key West should be your pick. No matter what your preference, there’s a perfect Florida Keys island for you!
The Florida Keys are a place full of natural wonders and amazing hotels. With so many options, it can be hard to decide which one is the best for your vacation. But here are seven of the best hotels in Florida Keys.
1. Reefhouse Resort & Marina
Location: Key Largo
3.5-star beachfront hotel with spa, near John Pennekamp Coral Reef State Park
If you’re looking for the best hotels in Florida Keys, look no further than Reefhouse Resort & Marina. This accommodation offers everything you need for a relaxing and enjoyable stay, from comfortable rooms and suites to on-site dining and world-class fishing.
The hotel is situated on a seven-acre private island and offers stunning waterfront views of the Atlantic Ocean. We’re also just minutes away from some of the most popular attractions in the area, including John Pennekamp Coral Reef State Park, Theater of the Sea, and Dolphins Plus Bayside.
We invite you to come experience all that our resort has to offer. Book your stay today and let us show you why we’re one of the best hotels in Florida Keys!

Guest review: “Gorgeous views and the room was more than expected. Staff was very welcoming and accommodating. One of the best hotels in Florida Keys. We would’ve loved to stay longer!“
2. Havana Cabana at Key West
Location: Key West
4-star hotel with outdoor pool, near Smathers Beach
The Havana Cabana Inn is one of the best hotels in Florida Keys. It’s centrally located in Key West, within walking distance of Duval Street and all the action. The inn has a variety of rooms available, from small efficiency studios to spacious two-bedroom apartments.
All of the rooms are decorated in a tropical style with bright colors and island accents. Amenities include air conditioning, cable TV, free WiFi, and a private balcony or patio. There’s also a heated pool and hot tub on site, as well as a bar and restaurant serving breakfast, lunch, and dinner daily.
The staff is friendly and helpful. They can provide you with information about the local attractions, and even book your favorite tours or excursions for you.

Guest review: “Amazing hotel – we only stayed one night but wish we were able to stay longer. Great rooms with super comfy beds, great pool, great staff and good pool bar/snack bar. Would definitely recommend this hotel if you’re heading to Key West. Thank you specifically to Annette and Kyle on the front desk, Dimitri at the pool bar and Nick, the pool attendant. The hotels offer a shuttle service for those who might be worried about whether it’s easy to reach Duval street!“
3. Faro Blanco Resort & Yacht Club
Location: Marathon
Bayfront hotel with 2 restaurants, near Pigeon Key Foundation
Looking for the best hotels in Florida Keys? Look no further than the Faro Blanco Resort & Yacht Club. This top-rated resort offers guests luxurious accommodations, fantastic amenities, and beautiful surroundings.
Located on a secluded stretch of white sand beach on Marathon Key, the Faro Blanco Resort & Yacht Club is the perfect place to relax and escape the hustle and bustle of everyday life. Guests can enjoy swimming in the crystal-clear waters of the Gulf, sunbathing on the beach, or exploring the area’s many attractions.
The resort also features a world-class marina with a wide variety of charter boats available for rental, making it easy to explore all that this wonderful part of Florida Keys has to offer.

Guest review: “Perfect location, beautiful modern hotel, big comfortable room, friendly and knowledgeable staff. Breakfast limited but delicious, good coffee. Just be aware there is a parking fee due to the property under fees, I did not see it. I would gladly stay there again.“
4. Margaritaville Beach House Key West
Location: Key West
4-star beach hotel with outdoor pool, near Smathers Beach
If you’re looking for a laid-back, beach-themed vacation, look no further than Margaritaville Beach House at Key West. This hotel is located right on the beach, so you can enjoy stunning ocean views and breezes from your room.
Considered as one of the best hotels in Florida Keys, this property is decorated with fun, island-inspired decor, and there are plenty of activities available on-site to keep you busy, including swimming, sunbathing, kayaking, and paddle boarding.
Plus, the staff is super friendly and happy to help make your stay as enjoyable as possible. If you’re looking for a relaxing escape to the Florida Keys, Margaritaville Beach House Key West is definitely worth considering.

Guest review: “Excellent midsized beach style hotel 10mins from downtown Key West. Coach service takes you in to KW each hour, which have friendly drivers giving you tips on where to eat, drink and enjoy. Service in the hotel is equally as friendly, with each genuinely engaging with guests. The rooms are well styled and modern and have plenty of inclusions such as all day coffee, shuttles, midday ice poles etc. Ate in the restaurant a few times and every meal was very good for hotel food. One of our favourite hotels over the course of our 6week drive through Florida, extending our 4 night stay to 10.. which came with a free upgrade.“
5. The Skipjack Resort & Marina Aparthotel
Location: Marathon
Riverfront aparthotel with outdoor pool, near Sombrero Beach
The Skipjack Resort & Marina Aparthotel is a great place to stay when visiting Florida. The hotel is in our list of best hotels in Florida Keys for more reasons. It is located on the beautiful St. John’s River and offers guests a variety of accommodations, including rooms and suites, as well as apart-hotels.
The property has an on-site restaurant and lounge, as well as a heated pool and spa. There is also a marina on-site, making it the perfect place to stay for those who love being on the water.
The Skipjack Resort & Marina Aparthotel is located in the historic city of Marathon, which offers a variety of shopping, dining, and nightlife. The area around the Skipjack Resort & Marina Aparthotel is also known for its fishing and boating.

Guest review: “Modern clean room with comfy bed and lots of space. Outside of the apartment looked a little tired but it didn’t affect our stay. Parking nearby. Breakfast is basic but there was lots of it and it was a nice touch. Didn’t use the pool but looked nice & had lots of space around for relaxing.“
6. Hawks Cay Resort
Location: Marathon
Marathon beachfront resort with 5 restaurants, spa
If you are looking for a luxurious and relaxing vacation spot in Florida Keys, look no further than Hawks Cay Resort. This resort offers guests some of the best accommodations in the state, with options ranging from cozy villas to spacious suites. You can also enjoy plenty of activities on-site, such as swimming, fishing, and kayaking. Plus, the resort is located in the heart of the Florida Keys, providing easy access to all the area has to offer.
The Hawks Cay Resort is located in Marathon, Florida. This smoke-free resort offers 292 guestrooms with private balconies or patios that overlook the ocean. Guests can enjoy five restaurants and three poolside bars on the property. There is also a private beach for guests to relax on.

Guest review: “Wonderful place if you are coming with a young family or large family and friends and do not plan on leaving. I guess I am not a resort person, typically plan on visiting local sights and activities. The resort fees are crazy! We would never get our Money’s worth.“
7. Oceans Edge Key West Resort, Hotel & Marina
Location: Key West
Waterfront hotel with 6 outdoor pools, near Key West Harbour
The Oceans Edge Key West Resort, Hotel & Marina is one of the best hotels in Florida Keys. It offers guests a wide variety of rooms and suites to choose from, all with beautiful waterfront views.
The on-site marina offers guests the opportunity to dock their boats right at the hotel, and there is also a heated pool and Jacuzzi for swimming and relaxing. The resort’s location in Key West puts guests just minutes away from all the island’s best attractions, including Duval Street, Hemingway’s Home, and the Southernmost Point in the United States.

Guest review: “Beautifully clean, tidy and luxurious resort. My only criticism would be that the balconies are so open you may as well be sitting with the people next door, no privacy at all.“
Conclusion
In conclusion, the best hotels in the Florida Keys are those that are situated on the water and have plenty of amenities. Visitors to the area should consider staying at one of these properties to make the most of their vacation.